Scrophularia orientalis extract induces calcium signaling and apoptosis in neuroblastoma cells

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Scrophularia orientalis extract induces calcium signaling and apoptosis in neuroblastoma cells

Effective neuroblastoma (NB) treatments are still limited despite treatment options available today. Therefore, this study attempted to identify novel plant extracts that have anticancer effects. Cytotoxicity and increased intracellular calcium levels were determined using the Sulforhodamine B (SRB) assay and Fluo4-AM (acetoxymethyl) staining and fluorescence microscopy in NB cells in order to ...

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ژورنال

عنوان ژورنال: International Journal of Oncology

سال: 2016

ISSN: 1019-6439,1791-2423

DOI: 10.3892/ijo.2016.3373